Publications
- See list of group theses.
- Papers:
2017, 2016, 2015, 2014, 2013, 2012, 2011, 2010, 2009, 2007, 2006, 2005, 2004, 2003, 2001, 2000, 1998, 1997, 1996, 1995, 1994, 1993, 1992, 1990, 1989, 1988, 1986, 1985, 1984.
- Transition from turbulent to coherent
flows in confined three-dimensional active fluids
Kun-Ta Wu, Jean Bernard Hishamunda, Daniel T. N. Chen, Stephen J. DeCamp, Ya-Wen Chang, Alberto Fernández-Nieves, Seth Fraden, Zvonimir Dogic
Science, eaal1979 (2017); DOI: 10.1126/science.aal1979
Perspective, Supplemental Materials: Supplement, Video 1, Video 2, Video 3, Video 4, Video 5, Video 6, Video 7, Video 8.
- Rapid prototyping of cyclic olefin copolymer (COC) microfluidic devices
S. Ali Aghvami, Achini Opathalage, Z.K. Zhang, Markus Ludwig, Michael Heymann, Michael Norton, Niya Wilkins, Seth Fraden
Sensors and Actuators B: Chemical, 247 (2017) 940-949; DOI: 10.1016/j.snb.2017.03.023
Supplemental Materials: Supplement, Video 1, Video 2, Video 3, Video 4, Video 5, Video 6, Video 7, Store then create Autocad, Al Mold Layer 1 Solidworks, Al Mold Layer 2 Solidworks, Cover Solidworks, Mold for Ferrule Solidworks.
- An
image-driven drop-on-demand system
C. Girabawe, S. Fraden
Sensors and Actuators B: Chemical, 238 (2017) 532-539; DOI: 10.1016/j.snb.2016.07.065
Supplemental Materials: Supplement, Video 1, Video 2, Video 3, Video 4
- Configurable NOR gate
arrays from Belousov-Zhabotinsky micro-droplets
A.L. Wang, J.M. Gold, N. Tompkins, M. Heymann, K.I. Harrington, S. Fraden
The European Physical Journal Special Topics 225 (1),211-227 (2016); DOI: 10.1140/epjst/e2016-02622-y
Supplemental Materials: Video 1, Video 2, Video 3, Video 4, Video 5, Matlab Code
- An inexpensive programmable
illumination microscope with active feedback
Nathan Tompkins and Seth Fraden
American Journal of Physics 84, 150 (2016); DOI: 10.1119/1.4935806
-
ATP Consumption of Eukaryotic Flagella Measured at a Single-Cell Level
Daniel T. N. Chen, Michael Heymann, Seth Fraden, Daniela Nicastro, and Zvonimir Dogic
Biophysical Journal 109, 2562-2573 (2015)
DOI: 10.1016/j.bpj.2015.11.003 - Low-Z polymer sample supports for
fixed-target serial femtosecond X-ray crystallography
G. K. Feld, M. Heymann, W. H. Benner, T. Pardini, C.-J. Tsai, S. Boutet, M. A. Coleman, M. S. Hunter, X. Li, M. Messerschmidt, A. Opthalage, B. Pedrini, G. J. Williams, B. A. Krantz, S. Fraden, S. Hau-Riege, J. E. Evans, B. W. Segelke and M. Frank
J. Appl. Cryst. 48, 1-8 (2015); DOI 10.1107/S16005767150104933
- Creation and perturbation of
planar networks of chemical oscillators
Nathan Tompkins, Matthew Carl Cambria, Adam L. Wang, Michael Heymann, and Seth Fraden
Chaos 25, 064611 (2015); DOI: 10.1063/1.4922056, Supplement and Video Captions
Supplemental Videos: SV1a, SV1d, SV1g, SV1j, SV3a, SV3c, SV4a, SV4b, SV4c, SV4d, SV6a, SV6b, SV6d, SVS1a (PDMS Mold Fabrication), SVS1b (Plastic Master Fabrication), SVS1c (Thin PDMS Device Fabrication), SVS2 (Clamping Procedure)
- Tunable diffusive
lateral inhibition in chemical cells
Ning Li, Nathan Tompkins, Hector Gonzalez-Ochoa and Seth Fraden
Eur. Phys. J. E 38, 18 (2015); DOI 10.1140/epje/i2015-15018-3
- A
simple and inexpensive device to remove edge beads, Markus
Ludwig and Seth Fraden, Chips
and Tips, 2015.
- DNA driven
self-assembly of micron-sized rods using DNA-grafted
bacteriophage fd virions
R. R. Unwin, R. A. Cabanas, T. Yanagishima, T. R. Blower, H. Takahashi, G. P. C. Salmond, J. M. Edwardson, S. Fraden and E. Eiser
Phys. Chem. Chem. Phys. 17, 8194-8202 (2015); Supplement; Movie. DOI: 10.1039/c4cp05405a
- Emulsion-Based
Technique To Measure Protein Crystal Nucleation Rates of
Lysozyme
Sathish V. Akella, Aaron Mowitz, Michael Heymann, and Seth Fraden
Crystal Growth & Design 14, 4487-4509 (2014); Movies:DOI: 10.1021/cg500562r
- Cross
polarization compatible dialysis chip,
Micha Kornreich, Michael Heymann, Seth Fraden and Roy Beck
Lab on a Chip 14, 3700-3704 (2014); DOI: 10.1039/c4lc00600c
- Room-temperature
serial crystallography using a kinetically optimized
microfluidic device for protein crystallization and on-chip
X-ray diffraction
Michael Heymann, Achini Opthalage, Jennifer L. Wierman, Sathish Akella, Doletha M. E. Szebenyi, Sol M. Gruner and Seth Fraden
IUCrJ (2014). 1, 349–360; doi:10.1107/S2052252514016960
- Giant Volume Change of Active
Gels under Continuous Flow,
Ye Zhang, Ning Zhou, Ning Li, Megan Sun, Dongshin Kim, Seth Fraden, Irving R. Epstein, and Bing Xu
JACS (2014); dx.doi.org/10.1021/ja503665t
Supplement; movie S1, oscillating gel annulus; movie S2, oscillating gel array.
- Combined excitatory and
inhibitory coupling in a 1D array of Belousov- Zhabotinsky
droplets
N. Li, J. Delgado, H. O. González-Ochoa, I. R. Epstein and S. Fraden
Phys. Chem. Chem. Phys. 16, 10965-10978 (2014); DOI:10.1039/C4CP00957F
- Testing Turing's Theory of
Morphogenesis in Chemical Cells
Nathan Tompkins, Ning Li, Camille Girabawe, Michael Heymann, G. Bard Ermentrout, Irving R. Epstein, and Seth Fraden
Proceedings of the National Academy of Sciences 111, 4397–4402 (2014); DOI: 10.1073/pnas.1322005111.
Supporting information: SI.pdf, SM01.mov, SM02.mov, SM03.mov, SM04.mov, SM05.mov, SM06.mov, SM07.mov
- Controlling
uniformity of photopolymerized microscopic hydrogels
Sukho Park, Dongshin Kim, Seong Young Ko, Jong-Oh Park, Sathish Akella, Bing Xu, Ye Zhang and Seth Fraden
Lab on a Chip, 14 (9), 1551 - 1563 (2014); DOI: 10.1039/c4lc00158c
Supporting information; Movie
S1, Movie
S2.
- Active
Cross-Linkers that Lead to Active Gels
Ye Zhang, Ning Zhou, Sathish Akella, Yi Kuang, Dongshin Kim, Alyssa Schwartz, Marc Bezpalko, Bruce M. Foxman, Seth Fraden, Irving R. Epstein, Bing Xu
Angewandte Chemie International Edition, 2013; DOI: 10.1002/anie.201304437.
Supporting information.
- Multi-Height
Precision Alignment With Selectively Developed Alignment Marks
Michael Heymann, Seth Fraden, and Dongshin Kim
Journal of Microelectromechanical Systems, 2013; DOI: 10.1109/JMEMS.2013.2279231.
- Structural
modulation of self-oscillating gels: changing the proximity of
the catalyst to the polymer backbone to tailor chemomechanical
oscillation
Ye Zhang, Ning Li, Jorge Delgado, Ning Zhou, Ryo Yoshida, Seth Fraden, Irving R. Epstein and Bing Xu
Soft Matter, 2012; DOI: 10.1039/c2sm25797a.
- Post-Self-Assembly
Cross-Linking of Molecular Nanofibers for Oscillatory Hydrogels
Ye Zhang, Ning Li, Jorge Delgado, Yuan Gao, Yi Kuang, Seth Fraden, Irving R. Epstein, and Bing Xu
Langmuir, 2012; DOI: 10.1021/la203923d.
- Interactions
between Colloids Induced by a Soft Cross-Linked Polymer
Substrate
Lorenzo Di Michele, Taiki Yanagishima, Anthony R. Brewer, Jurij Kotar, Erika Eiser and Seth Fraden
Physical Reveiw Letters 136101 (2011).
- Coupled
oscillations in a 1D emulsion of Belousov–Zhabotinsky droplets
Jorge Delgado, Ning Li, Marcin Leda, Hector O. Gonzalez-Ochoa, Seth Fraden and Irving R. Epstein
Soft Matter, 2011 ; DOI: 10.1039/c0sm01240h.
- Functional
patterning of PDMS microfluidic devices using integrated
chemo-masks
Mark B. Romanowsky, Michael Heymann, Adam R. Abate, Amber T. Krummel, Seth Fraden and David A. Weitz
Lab Chip, 2010, 10, 1521 - 1524, DOI: 10.1039/c004050a.
- Synchronization
of Chemical Micro-oscillators
Masahiro Toiya, Hector O. Gonzlez-Ochoa, Vladimir K. Vanag, Seth Fraden and Irving R. Epstein
J. Phys. Chem. Lett., 2010, 1 (8), pp 1241–1246; DOI: 10.1021/jz100238u. Check the supporting information here.
- Mapping and manipulating
temperature-concentration phase diagrams using microfluidics
Šeila Selimovic, Frédéric Gobeaux and Seth Fraden
Lab Chip, 2010, DOI : 10.1039/b925661j (link to supplementary data here).
- Phase
Behavior and Rheology of Attractive Rod Like Particles
F. Huang, R. Rotstein, Seth Fraden, Karen E Kasza and Nolan T. Flynn
Soft Matter, 2009, 5, 2766-2771.
- Measuring the
Nucleation Rate of Lysozyme using Microfluidics.
S. Selimovic, Y. Jia, and S. Fraden
Crystal Growth & Design, DOI: 10.1021/cg800990k (2009).
- Pair Potential
of Charged Colloidal Stars.
F. Huang, K. Addas, A. Ward, N.T. Flynn, E. Velasco, M.F. Hagan, Z. Dogic, and S. Fraden,
Physical Review Letters 102, 108302 (2009).
- Simple, robust storage
of drops and fluids in a microfluidic device
H. Boukellal, S. Selimovic, Y. Jia, G. Cristobal and S. Fraden,
Lab on a Chip 9, 331–338 (2009)
Movies! Lab on a Chip Supplementary Information.
- Using
microfluidics to decouple nucleation and growth of protein
crystals
J.U. Shim, G. Cristobal G, D.R. Link, T. Thorsen, S. Fraden,
Crystal Growth & Design 7, 2192-2194 (2007).
- Smectic ordering in
athermal systems of rodlike triblock copolymers,
S. Varga and S. Fraden
J. Chem. Phys. 127, 154902 (2007).
- Crystallization
conditions of membrane protein CLC-ec1: An example outside the
crystallization slot,
J. Blouwolff and S. Fraden
J. Crystal Growth 303, 546–553 (2007).
- Influence
of charge and flexibility on smectic phase formation in
filamentous virus suspensions,
K. Purdy and S. Fraden
Physical Review E 76, 011705 (2007).
- Control and
Measurement of the Phase Behavior of Aqueous Solutions Using
Microfluidics
J.U. Shim, G. Cristobal, D.R. Link, T. Thorsen, Y. Jia, K. Piattelli, S. Fraden,
J. Am. Chem. Soc. 129, 8825 - 8835 (2007); DOI: 10.1021/ja071820f
Supporting Information. Movies.
Selected by Science as an "Editors' Choice" and by Lab on a Chip as a "Research Highlight".
- The
coordination number of granular cylinders
J. Blouwolff and S. Fraden
Europhys. Lett., 76, 1095–1101 (2006).
- Phase Behavior of Rod-Like Viruses and Virus–Sphere Mixtures, Z. Dogic, Z. and S. Fraden, Chapter 1, in Soft Matter, Volume 2: Complex Colloidal Suspensions (eds G. Gompper and M. Schick), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany (2006). ISBN: 978-3-527-31369-3, DOI: 10.1002/9783527617067.ch1.
- Ordered phases of
filamentous viruses.
Z. Dogic and S. Fraden
Current Opinion in Colloid & Interface Science 11, 47 (2006).
- Light
scattering and phase behavior of Lysozyme-PEG mixtures.
J. Bloustine, T. Virmani, G. M. Thurston, and S. Fraden
Phys. Rev. Lett. 96, 087803 (2006).
- Nematic-nematic phase
separation in binary mixtures of thick and thin hard rods:
Results from Onsager-like theories.
S. Varga, K. Purdy, A. Galindo, S. Fraden, and G. Jackson
Phys Rev E 72, 051704 (2005).
- Nematic Phase transitions in
Mixtures of Thin and Thick Colloidal Rods.
K. R. Purdy, S. Varga, A. Galindo, G. Jackson, and S. Fraden
Phys. Rev. Lett. 94, 057801 (2005).
- Isotropic-cholesteric
phase transition of filamentous virus suspensions as a function
of rod length and charge.
K. R. Purdy and S. Fraden
Phys. Rev. E 70, 061703 (2004).
- Isotropic-Nematic phase
transition in suspensions of filamentous virus and the neutral
polymer Dextran.
Z. Dogic, K. Purdy, E. Grelet, M. Adams, and S. Fraden
Phys. Rev. E 69, 051702 (2004).
- Our lab mentioned in Science
News, Vol. 164, No. 1, July 5, 2003, p. 7.
Microbial Materials: Scientists co-opt viruses, bacteria, and fungi to build new structures.
- Measurements of
Protein-Protein Interactions by Size Exclusion Chromatography
J. Bloustine, V. Berejnov and S. Fraden
Biophysical Journal 85: 2619-2623 (2003).
- What is the origin of chirality
in the cholesteric phase of virus suspensions?
E. Grelet and S. Fraden
Phys. Rev. Lett. 90, 198302 (2003).
- Measuring the nematic order of
colloidal fd virus by x-ray diffraction
K. Purdy, Z. Dogic, S. Fraden. A. Ruehm, L. Lurio, and S. G. J. Mochrie
Phys. Rev. E. 67 031708 (2003).
- Development of model
colloidal liquid crystals and the kinetics of the
isotropic-smectic transition
Z. Dogic and S. Fraden
Philosophical Transactions of the Royal Society of London A 359, 997 - 1015 (2001).
- Self-Assembly in Vivo, with R.
Kamien
Biophys. J. 78, 2189 (2000).
- Enhanced stability of layered
phases in parallel hard-spherocylinders due to the addition of
hard spheres
Z. Dogic, D. Frenkel , S. Fraden
Physical Review E 62, 3925 - 3933 (2000).
- Concentration Dependent
Sedimentation of Colloidal Rods
Z. Dogic, A.P. Philipse, S. Fraden, and J.K.G. Dhont
J. Chem. Phys. 113, 8368 - 8380 (2000).
- Cholesteric Phase in Virus
Suspensions
Z. Dogic and S. Fraden
Langmuir 16, 7820 - 7824 (2000).
- Structure of Electrorheological
Fluids
U. Dassanayake, S. Fraden, and A. van Blaaderen
Journal of Chemical Physics 112, 3851- 3858 (2000).
- Entropically driven microphase
transitions in mixtures of colloidal rods and spheres.
Marie Adams, Zvonimir Dogic, Sarah L. Keller, and Seth Fraden
Nature 393: 349-352 (May 28, 1998).
- Another Face of Entropy
Peter Weiss
Science News, Aug. 15, 1998. News article on depletion, entropy, protein crystallization.
- Solving the
Poisson-Boltzmann equation to Obtain Interaction Energies
Between Confined, Like-Charged Cylinders
M. Ospeck and S. Fraden
J. Chem. Phys. 109, 9166 - 9171 (1998).
- Phase behavior of mixtures
of rods (Tobacco Mosaic Virus) and spheres (Polyethylene Oxide,
Bovine Serum Albumin)
Marie Adams and Seth Fraden
Biophysical Journal 74, 669-677 (1998).
- The Smectic Phase in a
Colloidal Suspension of Semi-Flexible Virus Particles
Zvonimir Dogic and Seth Fraden
Phys. Rev. Lett. 78, 2417-2420 (1997).
Download an adobe pdf copy of preprint
- Non-Monotonic
Temperature Dependence of the Flexibility of Bacteriophage fd
Jianxin Tang and Seth Fraden
Biopolymers 39, 13 - 22 (1996).
- Phase transitions in colloidal
suspensions of virus particles.
S. Fraden, M. Baus, L. F. Rull, and J. P. Ryckaert, editors
In "Observation, Prediction, and Simulation of Phase Transitions in Complex Fluids", NATO-ASI Series C, vol. 460, pages 113--164. Kluwer Academic Publishers, 1995.
- Isotropic-Cholesteric
phase transition in colloidal suspensions of bacteriophage fd
Jianxin Tang and Seth Fraden
Liquid Crystals 19, 459-467 (1995).
- Observation
and Simulation of Electro-Hydrodynamic Instabilities in Aqueous
colloidal Suspensions
Hu Y, Glass JL, Griffith AE, et al.
J Chem Phys, 100:4674 (1994).
- Video
microscopy study of the potential energy of a colloidal particle
confined between two plates.
G. M. Kepler and S. Fraden
Langmuir 10, 2501 - 2506 (1994).
- Attractive
potential between confined colloids at low ionic strength.
G. M. Kepler and S. Fraden
Phys. Rev. Letts. 73, 356 - 359 (1994).
- Influence
of Reflecting Boundaries and Finite Interfacial Thickness on the
Coherent Backscattering Cone
Ospeck M and Fraden S
Phys Rev E 49:4578 (1994).
- Angular
Correlations and the Isotropic-Nematic Phase Transition in
Suspensions of Tobacco Mosaic Virus
Fraden S, Maret G, and Caspar DLD
Phys Rev E 48:2816 (1993).
- Magnetic
Field Induced Isotropic-Nematic Phase Transition in a Colloidal
Suspension
Tang J and Fraden S
Phys Rev Lett, 71:3509 (1993).
- Liquidlike
Order of Charged Rodlike Particle Solutions
Maier EE, Krause R, Deggelmann M, et al.
Macromolecules 25:1125-33 (1992).
- Multiple
Light Scattering from Concentrated, Interacting Suspensions
Fraden S, Maret G.
Phys Rev Lett 65:512 (1990).
- Isotropic-Nematic
Phase Transition and Angular Correlations in Isotropic
Suspensions of Tobacco Mosaic Virus
Fraden S, Maret G, Caspar DLD
Phys Rev Lett 63:2068 (1989).
- Electric-field-induced
association of colloidal particles.
S. Fraden, A. J. Hurd, and R. B. Meyer
Phys. Rev. Letts. 63, 2373 - 2376 (1989).
- Field-Induced
Nonequilibrium Periodic Structures in Nematic Liquid Crystals:
Nonlinear Study of the Twist Frederiks Transition
Srajer G, Fraden S, Meyer RB.
Phys Rev A 39:4828 (1989).
- Comment
on `Measurement of the Viscoelastic Coefficients of main-Chain
Nematic Polymers by an NMR Technique'
Srajer G, Fraden S, Meyer RB.
Phys Rev Lett 61:899 (1988).
- Comment
on `Nonequilibrium Periodic Structures Induced by Rotating and
Static Fields in a Lyotropic Nematic Liquid Crystal'
Fraden S, Meyer RB.
Phys Rev Lett 57:3122 (1986).
- Magnetic
Field Induced Alignment and Instabilities in Ordered Colloids of
Tobacco Mosaic Virus
Fraden S, Hurd AJ, Meyer RB, et al.
J de Physique C3:85-113 (1985).
- Field
-Induced Transient Periodic Structures in Nematic Liquid
Crystals: the Splay Frederiks Transition
Hurd AJ, Fraden S, Lonberg F, et al.
J de Physique 46:905 (1985).
- Measurements
of the Anisotropic Viscous and Elastic Properties of Lyotropic
Polymer Nematics
Meyer RB, Lonberg F, Taratuta V, et al.
Faraday Discuss Chem Soc 79:125 (1985).
- Field-Induced
Transient Periodic Structures in Nematic Liquid Crystals: the
Twist Frederiks Transition
Lonberg F, Fraden S, Hurd AJ, et al.
Phys Rev Lett 52:1903 (1984).
Recent Graduate Theses
- X-ray Transparent
Microfluidics for Protein Crystallization and Biomineralization
Achini Opathalage (February 2016).
- Synchronization Dynamics
of Coupled Chemical Oscillators
Nathan Tompkins (April 2015).
- Nonlinear Chemical Dynamics
and Synchronization
Ning Li (October 2014).
- Microfluidic Tools
to Investigate Protein Crystallization
Michael Heymann (February 2014).
- Characterizing Protein
Crystal Nucleation
Sathish Akella (February 2014).
- Microfluidic
techniques for the study of Self-Assembly of Soft Materials
Rafael Aguade Cabanas (February 2014).
- Microfluidics for Protein
Crystallization and Mapping Phase Diagrams of Aqueous Solutions
Seila Selimovic (February 2010).
- Interactions and Collective
Behavior of Attractive Colloidal Rods and Microspheres Grafted
with Filamentous Bacteriophage
Phil Fei Huang (May 2009).
- Novel Approach to Protein
Crystallization; Control of the Phase Behavior of Aqueous
Solutions using Microfluidics
Jung uk Shim (February 2007).
- Experimental
Investigations into Interactions and Collective Behavior in
Protein/Polymer Mixtures and Granular Rods
Joshua David Bloustine (May 2006).
- Liquid Crystal Phase
Transitions in Mondisperse and Bidisperse Suspensions of Rodlike
Colloidal Virus
Kirstin R. Purdy (Aug. 2004).
- Liquid Crystalline Phase
Transitions in Virus and Virus/Polymer Suspensions
Zvonimir Dogic (Feb 2000).
Recent Undergraduate Theses
- Networks of Coupled
Chemical Oscillators
Matthew Carl Cambria (May 2015).
- Rapid Prototyping of 3D
Cyclic Olefin Copolymer (COC) Microfluidics Chip Using Hot
Embossing Method for Facilitating Protein Crystallization and
X-Ray Crystallography
Min-Sung (Chris) Hong (May 2015).
- Controlling Coupled Chemical
Oscillators: Toward Synchronization Engineering and Chemical
Computation
Adam L. Wang (May 2015).
- Inhibitively Coupled Chemical
Oscillators as a Substrate for Logic Gates and Larger Circuits
Jacob M. Gold (May 2015).
- A droplet based technique
to measure protein nucleation rates
Daniel Gerz (May 2014).
- Characterizing the
Crystallization of the D1D2 Heterodimer using Microfluidic
Devices
Markus Ludwig (May 2012).